Neurodegenerative disorders associated with genes of mitochondria

Abstract Background Over the last decade, aggregating evidences suggested that there is a causative link between mutation in gene associated with mitochondrial dysfunction and development of several neurodegenerative disorders. Main text Recent structural functional studies genes have shown abnormalities possibly lead to dysfunction. Several on animal models diseases provided compelling evidence mitochondria involved initiation as well progression such Parkinson’s disease (PD), Alzheimer’s (AD), Huntington’s (HD), Friedreich ataxia (FA). Conclusion In this mini-review, we discussed different etiologic pathogenesis connected relevant underlie dominant part its progress.